Table 6 Metastasis-free survival analysis (N = 20).

From: IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

Factor

Patients

Events (metastasis)

Median (months)

P-value (log rank test)

Age at diagnosis (years)

 ≤ 15

6

4

11.1

0.984

 > 15

14

9

9.7

Gender

Male

11

10

8.9

0.027

Female

9

3

Undefined

Enneking stage

IIB

18

11

10.8

< 0.001

III

2

2

1.2

Site

Extremities

16

11

9.5

0.478

Axial

4

2

24.2

IMPDH2 expression

Low (IRS ≤ 6)

6

2

Undefined

0.030

High (IRS > 6)

14

11

6.9

HPRT expression

Low (IRS ≤ 6)

9

5

11.5

0.640

High (IRS > 6)

11

8

9.3

IMPDH2/HPRT ratio

Low IMPDH2/HPRT

16

11

9.1

0.472

High IMPDH2/HPRT

4

2

53.4

  1. P values were calculated using the log-rank test. P values < 0.05 shown in bold.
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