Table 7 Multivariate analysis of metastasis-free survival in osteosarcoma patients and IMPDH2 expression in post-chemotherapy tissues (n = 20).

From: IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

Factor

Overall survival

HR (95% CI)

P value

Age at diagnosis (years)

 ≤ 15

1.00

–

 > 15

0.66 (0.15–2.84)

0.576

Gender

Male

1.00

–

Female

0.21 (0.05–0.88)

0.033

Site

Extremities

1.00

–

Axial

0.71 (0.14–3.73)

0.687

IMPDH2 expression

Low (IRS ≤ 6)

1.00

–

High (IRS > 6)

7.42 (1.22–45.06)

0.030

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