Table 8 Multivariate analysis of metastasis-free survival in osteosarcoma patients and HPRT expression in post-chemotherapy tissues (n = 20).

From: IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

Factor

Overall survival

HR (95% CI)

P value

Age at diagnosis (years)

 ≤ 15

1.00

–

 > 15

1.69 (0.47–6.11)

0.423

Gender

Male

1.00

–

Female

0.24 (0.06–0.95)

0.042

Site

Extremities

1.00

–

Axial

0.58 (0.12–2.96)

0.517

HPRT expression

Low (IRS ≤ 6)

1.00

–

High (IRS > 6)

1.07 (0.32–3.55)

0.909

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