Table 9 Multivariate analysis of metastasis-free survival in osteosarcoma patients and IMPDH2/HPRT ratio in post-chemotherapy tissues (n = 20).

From: IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

Factor

Overall survival

HR (95% CI)

P value

Age at diagnosis (years)

 ≤ 15

1.00

–

 > 15

2.22 (0.56–8.84)

0.257

Gender

Male

1.00

–

Female

0.25 (0.06–1.00)

0.051

Site

Extremities

1.00

–

Axial

0.45 (0.08–2.38)

0.348

IMPDH2/HPRT ratio

Low IMPDH2/HPRT

1.00

–

High IMPDH2/HPRT

0.47 (0.08–2.55)

0.380

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