Table 1 Baseline characteristic of the validation cohort.

From: Identification of BHLHE40 expression in peripheral blood mononuclear cells as a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma

Baseline characteristics

Healthy controls (n = 100)

Patients without HCC (n = 100)

Patients with HCC (n = 100)

P

Age (years)

56.3 ± 3.4

56.7 ± 8.4

57.7 ± 8.6

0.053

Gender (Male)

80 (80.0)

85 (85.0)

85 (85.0)

0.549

Total bilirubin (mg/dL)

 

0.9 ± 0.7

1.0 ± 0.7

0.729

Serum albumin (g/dL)

 

4.1 ± 0.6

3.6 ± 0.5

 < 0.001*

Aspartate aminotransferase (IU/L)

 

36.6 ± 30.2

64.5 ± 53.5

 < 0.001*

Alanine aminotransferase (IU/L)

 

42.9 ± 42.3

44.8 ± 25.8

0.709

Alkaline phosphatase (IU/L)

 

77.3 ± 50.6

125.3 ± 70.8

 < 0.001*

Platelet count (109/L)

 

223.2 ± 74.6

176.0 ± 93.9

0.002*

Alpha fetoprotein (ng/mL)

 

8.5 ± 13.9

6928.1 ± 28,444.2

0.016*

Presence of cirrhosis

 

11 (11.0)

80 (80.0)

 < 0.001*

BCLC stage (0-A/B/C)

 

-

35(35.0)/50(50.0)/15(15.0)

-