Figure 2
From: Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection
Dynamics of the SARS-CoV-2-perturbed network for different viral loads in host cells. (A) The histograms of \(\Delta \)ECv for different SARS-CoV-2 viral loads; a low MOI of 0.2 (blue) and a high MOI of 2 (magenta). The X-axis corresponds to the threshold for each \(\Delta \)ECv. The Y-axis shows the number of edges on a log scale. (B) The Venn diagram represents the numbers of differentially regulated edges (DREs) for two SARS-CoV-2 viral loads (blue: low MOI, magenta: high MOI) with a threshold of 1.0 for \(\Delta \)ECv in Fig. 2A. (C) The top 10 terms of canonical pathway analysis for the genes comprising a union set of \(\Delta \)ECv-extracted DREs in the Venn diagram analysis (Fig. 2B). (D) The whole illustration for the subnetwork fragments of various sizes is shown. Image of how the \(\Delta \)ECv-extracted DREs mutually connected and generated the subnetworks.
