Figure 2

Each box represents a patient, differentiating the ones infected by the successfully transmitted variant (Variant 1, coloured in dark grey) from those infected by unsuccessfully transmitted closely related variants (in light grey). Patient´s origin is indicated within the box and the year of diagnosis in brackets. When two or more cases share identical sequences (0 SNPs between them) they are boxed, surrounded by a line. Each black dot represents a SNP. The white circles in Variant 1 branch correspond to non-fixed alleles, found in heterozygosis in the index case (Morocco-2011) but in homozygosis in the remaining cases. In the white boxes the name of the variant is indicated (Var). mv median vectors (corresponding to not-sampled nodes).