Table 3 Sample size calculation.

Detected differences in volumetric indices	Observer A		Observer B		Automated
Detected differences in volumetric indices	SD	Sample size	SD	Sample Size	SD	Sample Size
Left ventricle
10 g Mass	5.35	5	15.78	40	7.55	9
10 ml EDV	6.51	7	23.76	89	14.09	32
10 ml ESV	8.01	11	14.69	34	9.94	16
10 ml SV	6.39	7	15.21	37	9.29	14
5% EF	2.98	6	5.40	19	3.01	6
Right ventricle
10 ml RV EDV	6.72	8	17.70	50	22.12	77
10 ml RV ESV	5.97	6	16.29	42	13.07	27
10 ml RV SV	7.49	9	21.56	73	19.56	61
5% RV EF	3.51	8	10.50	70	7.12	32

Sample size calculation for repeated measurements of left and right ventricular volumes for the detection of changes amounting to 10 g mass, 10 ml volumes and 5% EF respectively.
EDV end-diastolic volume, ESV end-systolic volume, SV stroke volume, EF ejection fraction, SD standard deviation.

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