Table 3 Association of GWA findings on BP traits in UKbiobank and Japanese population.
Locus nearby | Position | rs ID | Effect/other allele | UKbiobank | Japanese pop | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EAF | HTN | DBP | SBP | EAF | DBP | SBP | |||||||||
β (se) | P value | β (se) | P value | β (se) | P value | β (se) | P value | β (se) | P value | ||||||
FBN1 | 15:48420560 | rs2303505 | T/G | 0.008 | 7.2E−03 (5.5E−03) | 1.9E−01 | 1.5E−02 (1.3E−02) | 2.4E−01 | 2.3E−03 (1.2E−02) | 8.4E−01 | 0.13 | − 2.9E−03 (5.3E−03) | 6.0E−01 | − 6.3E−03 (5.6E−03) | 2.6E−01 |
15:48428455 | rs363830 | T/C | 0.017 | 8.8E−03 (3.8E−03) | 2.1E−02 | 2.3E−03 (9.2E−03) | 7.9E−01 | − 1.8E−04 (8.7E−03) | 9.8E−01 | 0.13 | 3.0E−03 (5.6E−03) | 5.9E−01 | − 1.8E−04 (8.7E−03) | 9.8E−01 | |
15:48420679 | rs363838 | G/T | 0.02 | 7.0E−03 (5.5E−03) | 2.0E−01 | 1.5E−02 (1.3E−02) | 2.5E−01 | 2.6E−03 (1.2E−02) | 8.3E−01 | 0.13 | − 2.9E−03 (5.6E−03) | 6.0E−01 | − 6.3E−03 (5.6E−03) | 2.6E−01 | |
ABHD17C | 15:80717774 | rs1078107 | C/T | 0.003 | − 1.3E−02 (8.4E−03) | 1.0E−01 | − 4.2E−02 (2.0E−02) | 3.2E−02 | − 2.6E−02 (1.9E−02) | 1.6E−01 | 0.07 | − 9.5E−02 (7.2E−03) | 1.9E−01 | − 4.7E−03 (7.2E−03) | 5.1E−01 |
15:80689205 | rs16972291 | C/T | 0.003 | − 1.2E−02 (8.7E−03) | 1.6E−01 | − 3.9E−02 (2.0E−02) | 5.6E−02 | − 2.5E−02 (1.9E−02) | 2.0E−01 | 0.04 | − 1.4E−02 (8.8E−03) | 1.0E−01 | 3.3E−03 (8.8E−03) | 7.0E−01 | |
ZBED9 | 6:28574647 | rs450630 | A/G | 0.46 | − 3.6E−03 (1.0E−03) | 2.5E−04 | − 1.5E−02 (2.3E−03) | 2.4E−10 | 6.2E−05 (2.2E−03) | 9.7E−01 | 0.33 | 1.7E−03 (4.0E−03) | 6.8E−01 | 5.0E−03 (4.0E−03) | 2.1E−01 |
6:28611694 | rs9501180 | T/C | 0.47 | 3.9E−03 (1.0E−03) | 9.5E−05 | 1.5E−02 (2.3E−03) | 2.3E−10 | − 1.3E−04 (2.2E−03) | 9.5E−01 | 0.33 | 1.9E−03 (4.0E−03) | 6.3E−01 | 5.0E−03 (4.0E−03) | 2.1E−01 | |
6:28602172 | rs380914 | T/C | 0.47 | − 3.7E−03 (1.0E−03) | 1.6E−04 | − 1.4E−02 (2.3E−03) | 3.4E−10 | 5.2E−04 (2.2E−03) | 8.1E−01 | 0.33 | 1.9E−03 (4.0E−03) | 6.4E−01 | 4.9E−03 (4.0E−03) | 2.2E−01 | |
6:28554918 | rs6456825 | G/A | 0.46 | − 3.8E−03 (1.0E−03) | 1.1E−04 | − 1.5E−02 (2.3E−03) | 1.3E−10 | − 8. 9E−05 (2.2E−03) | 9.6E−01 | 0.33 | 1.8E−03 (4.0E−03) | 6.5E−01 | 5.1E−03 (4.0E−03) | 2.0E−01 | |
6:28682576 | rs9885928 | A/G | 0.49 | − 3.6E−03 (1.0E−03) | 3.3E−04 | − 1.3E−02 (2.3E−03) | 2.3E−08 | − 1.2E−03 (2.2E−03) | 5.8E−01 | 0.43 | 2.1E−03 (4.0E−03) | 6.0E−01 | 5.7E−03 (4.0E−03) | 1.6E−01 | |
