Figure 2 | Scientific Reports

Figure 2

From: An initial assessment of the involvement of transglutaminase2 in eosinophilic bronchitis using a disease model developed in C57BL/6 mice

Figure 2

IgE concentration in sera and lung pathology score are significantly increased after OVA intranasal challenges. (a) IgE levels in mice sera were all elevated after OVA administration at all doses. (b) Lung pathology score according to calibrated criteria (Table 1) from indicated C57BL/6 mice under hematoxylin and eosin staining. (c) Representative photographs of (b), 200 × , insets show infiltrated eosinophils (red) around terminal bronchioles. (25 µg OVA dose, n = 5, other groups, n ≥ 9. *P ≤ 0.05; **P < 0.01; ***P < 0.001). The scale is indicated on the panel by the length of the box around the size in µm.

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