Table 1 Lung pathology scoring system.

From: An initial assessment of the involvement of transglutaminase2 in eosinophilic bronchitis using a disease model developed in C57BL/6 mice

Lung pathology

Score

(1) No lesions

0

(2) Areas of inflammation

(a) In peribronchiole or perivascule

1

(b) a + alveolar lumen and alveolar wall

2

(c) b + exudates in bronchi/bronchiolar lumen

3

(3) Extent of immune cell infiltration including eosinophilic inflammation

(a) Some sporadic immune cell infiltration without eosinophils

1

(b) Some immune cell infiltration with few eosinophils

2

(c) Some patchy immune cell foci with apparent eosinophils

3

(d) Multiple immune cell foci with vast eosinophils

4

(4) Area ratio of exudates in bronchi/bronchiolar lumen

(a) Greater than 5% but less than one-third

2

(b) Between one-third and two-thirds

3

(c) Greater than two-thirds

4

(5) Magnitude of inflammatory foci in the lung

(a) Some small patchy inflammatory foci

2

(b) Some large patchy inflammatory foci existed in less than one-third of the whole lung section

3

(c) Confluent inflammatory foci existed in one-third to two-thirds of the whole lung section

4

(d) Confluent inflammatory foci existed in more than two-thirds of the whole lung section

5