Table 2 Differential gene enriched in Alzheimer's disease.

From: Analysis of the role of Purα in the pathogenesis of Alzheimer's disease based on RNA-seq and ChIP-seq

Gene ID

Gene name

HT22 (count)

Purα-ko (count)

FDR

log2FC

Regulated

ENSMUSG00000015568

Lpl

1138

554

4.20E–05

 − 1.08

Down

ENSMUSG00000018411

Mapt

25

87

8.02E–05

1.76

Up

ENSMUSG00000027820

Mme

361

86

7.48E–13

 − 2.11

Down

ENSMUSG00000035674

Ndufa3

621

1178

0.001

0.89

Up

ENSMUSG00000040249

Lrp1

7916

4904

0.006

 − 0.73

Down

ENSMUSG00000057666

Gapdh

6112

3641

0.003

 − 0.78

Down

ENSMUSG00000064358

mt-Co3

1381

778

0.001

 − 0.87

Down