Table 2 T-, B- and NK-lymphocyte subpopulation relative and absolute counts at baseline in survivors and nonsurvivors.

From: Baseline T-lymphocyte subset absolute counts can predict both outcome and severity in SARS-CoV-2 infected patients: a single center study

 

Survivors (N = 126; 78.7%)

Nonsurvivors (N = 34; 21.3%)

p

All patients (N = 160)

Parameter

Median [IQR]

Median [IQR]

 

Median [IQR]

CD3+ %

73.39 [67.98–79.84]

64.40 [57.96–70.10]

< 0.001

72.03 [65.62–79.35]

CD3+ #

825.50 [575.25–1294.25]

397.00 [283.00–626.00]

< 0.001

767.00 [480.50–1134.50]

CD3 + CD4+ %

45.34 [37.75–51.17]

40.78 [32.29–47.85]

0.10

44.20 [36.64–50.98]

CD3 + CD4+ #

521.00 [371.50–772.25]

247.00 [195.00–365.00]

< 0.001

470.50 [293.00–718.75]

CD3 + CD8+ %

25.00 [18.56–29.79]

22.05 [12.11–26.80]

0.03

23.75 [17.25–29.63]

CD3 + CD8+ #

292.50 [168.25–459.50]

127.00 [67.50–210.25]

< 0.001

242.00 [137.75–419.00]

CD3 + CD4 + CD8+ %

0.82 [0.55–1.34]

0.71 [0.39–0.92]

0.04

0.80 [0.55–1.32]

CD3 + CD4 + CD8+ #

10.00 [6.00–18.00]

4.00 [3.00–6.75]

< 0.001

9.00 [5.00–16.00]

CD3 + CD4 − CD8− %

2.73 [1.81–3.83]

1.64 [0.79–2.63]

< 0.001

2.49 [1.54–3.61]

CD3 + CD4 − CD8− #

28.50 [18.25–52.75]

12.00 [6.00–20.00]

< 0.001

26.00 [15.00–47.00]

CD19+ %

10.45 [7.40–14.46]

13.52 [9.18–22.36]

0.03

11.22 [7.51–15.43]

CD19+ #

118.50 [74.50–187.75]

97.00 [64.25–162.25]

0.17

116.00 [70.75–180.75]

CD3negCD16 + CD56+ %

13.11 [8.76–17.95]

16.99 [9.40–27.69]

0.08

13.59 [9.05–19.20]

CD3negCD16 + CD56+ #

145.50 [99.00–226.50]

101.00 [61.00–236.00]

0.05

137.00 [91.50–227.75]

CD4/CD8 ratio

1.79 [1.37–2.70]

2.04 [1.17–4.15]

0.32

1.84 [1.34–2.79]

  1. Statistically significant p values are highlited in bold.
  2. Reference values: CD3+ (%): 55–84; CD3+ (cells/µl): 690–2540; CD3 + CD4+ (%): 31–60; CD3 + CD4+ (cells/µl): 410–1590; CD3 + CD8+ (%): 13–41; CD3 + CD8+ (cells/µl): 190–1140; CD19+ (%): 5–25; CD19+ (cells/µl): 90–660; CD3negCD16 + CD56+ (%): 5–27; CD3negCD16 + CD56+ (cells/µl): 90–590; CD4/CD8 ratio: 1.5–2.5
  3. Subpopulation relative counts are expressed as the percentages of total lymphocytes.
  4. Differences between groups were assessed using the Mann–Whitney U test. A two-sided p value of < 0.05 was considered statistically significant.
  5. IQR interquartile range.
Back to article page