Table 5 Laboratory parameters at baseline after patient stratification according to maximal oxygen supply/ventilation support.

From: Baseline T-lymphocyte subset absolute counts can predict both outcome and severity in SARS-CoV-2 infected patients: a single center study

Parameter

AA (N = 68; 42.5%)

VMK (N = 20; 12.5%)

NRM (N = 26; 16.2%)

NIV (N = 27; 16.9%)

OTI (N = 19; 11.9%)

p

 

Median [IQR]

Median [IQR]

Median [IQR]

Median [IQR]

Median [IQR]

 

Hb (g/dl)

13.20 [12.28–14.35]

12.300 [11.030–13.300]

12.65 [10.60–13.75]

13.40 [11.00–14.55]

11.900 [9.750–13.500]

0.07

Plt (/µl)

221,500 [175000–288000]

198,000 [165750–265000]

202,500 [122500–259250]

212,000 [160500–281500]

236,000 [138000–277500]

0.60

WBC (/µl)

5330 [4027–7018]

6610 [5110–8320]

7060 [5003–10107]

5610 [4260–6920]

6600 [3760–11210]

0.035

Neut (/µl)

3210 [2308–4503]

4680 [3450–7120]

5685 [3913–8865]

4400 [2560–5800]

5280 [2485–8880]

 < 0.001

Ly (/µl)

1300 [918–1810]

1220 [1000–1460]

840 [692–1353]

960 [670–1230]

630 [430–1150]

 < 0.001

N/L ratio

2.33 [1.41–3.84]

3.69 [2.32–6.69]

7.32 [3.92–13.07]

3.88 [2.52–9.16]

6.77 [4.15–16.38]

 < 0.001

CRP (mg/l)

23.05 [10.33–55.48]

90.70 [39.72–141.30]

101.20 [46.45–147.10]

53.40 [17.38–109.65]

77.80 [57.80–125.30]

 < 0.001

LDH (IU/l)

232.00 [180.00–290.00]

273.00 [226.25–355.25]

333.00 [254.00–415.00]

311.50 [248.00–356.50]

341.00 [283.00–501.50]

 < 0.001

CPK (IU/l)

76.50 [49.00–152.50]

133.00 [97.00–195.50]

122.00 [49.25–254.00]

83.00 [55.00–191.00]

79.50 [50.50–135.75]

0.16

AST (IU/l)

26.00 [21.00–35.00]

35.00 [24.75–46.25]

38.00 [31.00–42.00]

39.00 [28.00–51.75]

31.00 [24.50–70.50]

0.015

ALT (IU/l)

22.00 [16.00–33.00]

17.50 [12.00–37.00]

21.50 [14.00–30.00]

30.00 [14.50–60.75]

24.00 [14.00–43.50]

0.53

Conj Bil (mg/dl)

0.33 [0.24–0.41]

0.32 [0.26–0.45]

0.38 [0.32–0.51]

0.30 [0.23–0.44]

0.36 [0.28–0.47]

0.13

Total Bil (mg/dl)

0.62 [0.48–0.86]

0.65 [0.43–0.83]

0.67 [0.52–0.92]

0.64 [0.49–1.00]

0.66 [0.51–0.81]

0.94

Creatinine (mg/dl)

0.89 [0.77–1.04]

0.99 [0.82–1.77]

1.08 [0.87–1.66]

0.85 [0.73–1.06]

1.22 [0.95–2.31]

 < 0.001

IL6 (pg/ml)

19.60 [7.82–34.32]

28.75 [18.60–55.25]

46.70 [20.90–90.95]

44.10 [30.10–69.70]

39.05 [21.32–92.65]

 < 0.001

TNF alpha (pg/ml)

31.96 [12.92–52.92]

17.47 [13.46–31.10]

30.67 [19.05–46.41]

14.81 [10.27–19.78]

24.35 [11.11–34.37]

0.021

D-Dimers (ng/ml)

678.50 [410.75–1143.75]

964.00 [649.25–2530.00]

1370.00 [967.00–2980.75]

907.00 [531.50–1867.50]

1636.00 [1060.50–5442.50]

 < 0.001

Fibrinogen (mg/dl)

467.00 [389.50–604.00]

555.00 [475.00–682.25]

612.50 [454.00–725.00]

597.00 [435.00–692.00]

579.00 [469.00–740.00]

0.064

INR

1.12 [1.08–1.22]

1.19 [1.12–1.28]

1.19 [1.09–1.25]

1.17 [1.08–1.24]

1.22 [1.14–1.27]

0.10

PT (seconds)

13.80 [13.23–15.10]

14.70 [13.78–15.82]

14.55 [13.35–15.35]

14.40 [13.25–15.30]

15.10 [13.95–15.75]

0.08

PT (%)

75.50 [68.00–85.00]

73.50 [60.75–79.00]

71.50 [67.25–78.75]

73.50 [65.25–81.00]

67.00 [62.00–79.50]

0.16

  1. Statistically significant p values are highlited in bold.
  2. Reference values: Hb (g/dl): 12.00–16.00; Plt (/µl): 150,000–450,000; WBC (/µl): 4300–10,800; CRP (mg/l): 0–5.00; LDH (IU/l): 125.00–220.00; CPK (IU/l): 29.00–168.00; AST (IU/l): 5.00–34.00; ALT (IU/l): 0–55.00; Conj Bil (mg/dl): < 0.50; Total Bil (mg/dl): < 1.20; Creatinine (mg/dl): 0.55–1.02; IL-6 (pg/ml): < 50; TNF-alpha (pg/ml): < 12.4; D-Dimers (ng/ml): 0–500.00; Fibrinogen (mg/dl): 200.00–400.00; INR: 0.80–1.20; PT (%): 70.00–130.00.
  3. Differences between groups were assessed using the Kruskal–Wallis test. A two-sided p value of < 0.05 was considered statistically significant.
  4. Hb hemoglobin, Plt platelets, WBC white blood cell, Neut neutrophils, Ly lymphocyte, N/L ratio neutrophil-to-lymphocyte ratio, CRP C-reactive protein, LDH lactate dehydrogenase, CPK creatine-phosphokinase, AST aspartate transaminase, ALT alanine transaminase, Conj Bil Conjugated bilirubin, Total Bil total bilirubin, IL-6 interleukin-6, TNF-alpha tumor necrosis factor-alpha, INR international normalized ratio, PT prothrombin time.
Back to article page