Table 2 Risk factors for 100-day mortality in multiple myeloma patients receiving ASCT.

From: The influence of high-efficiency particulate air filtration on mortality among multiple myeloma patients receiving autologous stem cell transplantation

Predictive variables

Univariate analysis

Multivariate analysisa

HR (95% CI)

P value

HR (95% CI)

P value

HEPA group

1.39 (0.44–4.37)

0.576

1.65 (0.52–5.23)

0.399

Age ≥ 60 years

0.93 (0.28–3.08)

0.902

  

Sex (male)

1.17 (0.37–3.69)

0.789

  

Duration from MM to HSCT ≥ 180 days

0.88 (0.26–2.92)

0.832

  

Comorbidities

Atrial fibrillation

4.28 (0.55–33.14)

0.164

  

Coronary artery disease

5.80 (1.75–19.27)

0.004

5.42 (1.63–18.02)

0.006

Liver cirrhosis

*

   

COPD

0.89 (0.24–3.31)

0.868

  

Cerebrovascular accident

1.54 (0.34–7.04)

0.576

  

Diabetes mellitus

1.78 (0.57–5.61)

0.324

  

Hypertension

1.97 (0.59–6.56)

0.266

  

ESRD

5.46 (1.76–16.93)

0.003

5.33 (1.70–16.68)

0.004

Heart failure

1.85 (0.41–8.44)

0.428

  

Ischemic stroke

1.11 (0.14–8.56)

0.924

  

Autoimmune disease

1.96 (0.43–8.94)

0.385

  

Degree of urbanization

Urban

Reference

   

Suburban

1.03 (0.30–3.52)

0.961

  

Rural

1.59 (0.20–12.93)

0.664

  

Income level

Low

Reference

   

Intermediate

*

   

High

*

   
  1. ASCT autologous stem cell transplantation; HR hazard ratio; CI confidence interval; COPD chronic obstructive pulmonary disease; ESRD end-stage renal disease.
  2. aAll factors with p < 0.1 in the univariate analysis were included in the Cox multivariate analysis. *Do not converge