Figure 3
From: Development of anti-thrombotic vaccine against human S100A9 in rhesus monkey

Effect of S100A9 vaccination on thrombus formation. (A) Thrombus formation in the mixture of fresh plasma and pre-vaccinated (dotted line) and post-vaccinated (line) serum was evaluated under laminar flow with collagen (T-TAS). (B) The AUC in (A) was calculated. The post-vaccinated serum from monkeys No. 1 and No. 4 shows a delay in thrombus formation. Data represent the mean ± SEM of 3 times measurements in each group. *Mann–Whitney test, p < 0.05 vs. pre-vaccinated monkey. T-TAS, total thrombus formation analysis system.