Figure 4 | Scientific Reports

Figure 4

From: Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients

Figure 4

Analysis of PPI interaction and hub genes identification. (A) Co-expression networks and sub-modules using WGCNA (Weighted correlation network analysis) of DEGs on iDEP 9.0 (http://bioinformatics.sdstate.edu/idep/) generates modules of the top 10 highly correlated genes. (B) Identification of significant hub genes from DEGs using DMNC and MCC algorithm on Cytoscape 3.7.1. Color represents the ranked hub genes on Cytoscape based on the corrected p value. (C) Venn analysis of both sets of hub genes to find common significant hub genes (http://bioinformatics.psb.ugent.be/webtools/Venn/).

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