Table 1 Population characteristics.

From: Hemodynamic and biological correlates of glomerular hyperfiltration in sickle cell patients before and under renin–angiotensin system blocker

Clinical parameters

N = 37

Age (years)

31.1 ± 7.7

BMI (kg/m2)

22.4 ± 3.2

Gender (M/F)

14/23

Ulcer (%)

8.1%

ACS (%)

77%

Retinopathy (%)

24%

Priapism (% males)

28.6%

Hydroxycarbamide (%)

35.1%

Hemodynam ic parameters

SBP (mmHg)

111 ± 9.3

DBP (mmHg)

57 ± 7.0

MAP (mmHg)

75 ± 7.1

HR (beats/min)

73 ± 9.7

PP (mmHg)

53 ± 7.0

PW V (m/s)

8.0 ± 1.2

CI (l/min/m2)

4.6 ± 0.7

LVMI (g/m2)

110 ± 21.1

TRV (m/s)

2.50 ± 0.18

SVR (dynes/s/cm−5)

759 ± 151

Biological parameters

Creatinine (µmol/l)

46.6 ± 12.3

ACR (mg/mmol)

47.8 ± 52.0

Hb (g/dl)

8.4 ± 1.1

Reticulocyte (103/mm3)

303 ± 141

Bilirubin (UI/l)

65 ± 42

LDH (UI/l)

478 ± 122

ADMA (µmol/l)

1.07 ± 0.45

Fasting glucose (mmol/l)

4.90 ± 0.43

Fasting insulin (mUI/l)

4.58 ± 2.7

  1. BMI: body mass index; ACS: acute chest syndrome; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; HR: heart rate; PP: pulse pressure; PWV: pulse wave velocity; CI: cardiac index; LVMI: left ventricular mass index; TRV: tricuspid regurgitation velocity; SVR: systemic vascular resistance; ACR: albumin creatinine ratio; Hb: haemoglobin; LDH: lactic dehydrogenase; ADMA: asymetric dimethyl arginine.
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