Table 1 Simple linear regression evaluating the association between variables with pretransfusion or peak KIM-1 levels.
From: Changes in urinary kidney injury molecule-1 levels after blood transfusions in preterm infants
Variable | Association with pretransfusion KIM-1 Levels | Association with peak KIM-1 Levels | ||
|---|---|---|---|---|
b coefficient | p value | b coefficient | p value | |
Gestational age, 25 (24, 28) weeks | − 0.01 | 0.83 | − 0.01 | 0.88 |
Gender, male n = 15 | − 0.62 | 0.09 | − 0.48 | 0.12 |
Race, Black n = 25 | 0.43 | 0.3 | 0.42 | 0.21 |
Birth weight, 865 (± 375) g | 0.01 | 0.3 | 0.01 | 0.96 |
PMA at transfusion, 31 (± 5) weeks | − 0.04 | 0.36 | 0.02 | 0.57 |
Age at transfusion, 29 (20, 47) days | − 0.01 | 0.32 | 0.01 | 0.2 |
Serum creatinine, 0.4 (0.4, 0.5) mg/dl | − 0.52 | 0.49 | − 0.43 | 0.48 |
Prior history of acute kidney injury, n = 4 | − 0.6 | 0.3 | − 0.49 | 0.29 |
Transfusions in preceding 48 h, n = 2 | 0.21 | 0.79 | 0.24 | 0.71 |
Pretransfusion KIM-1, 2270 (830, 3250) pg/mg | 1 | < 0.01 | 0.36 | < 0.01 |
FiO2, 30 (21, 40) % | 0.01 | 0.33 | 0.01 | 0.53 |
Respiratory severity score, 4.1 (3.3, 6.8) | 0.05 | 0.66 | 0.01 | 0.9 |
Intubated, n = 14 | 0.08 | 0.83 | 0.13 | 0.67 |
Antibiotics in preceding 72 h, n = 12 | − 0.03 | 0.94 | 0.2 | 0.54 |
Diuretics in preceding 48 h, n = 15 | − 0.04 | 0.91 | 0.1 | 0.76 |
Hematocrit at transfusion, 27 (± 4) % | 0.05 | 0.36 | 0.04 | 0.42 |
Volume of transfusion, ml/kg | 0.17 | 0.03 | − 0.05 | 0.46 |
