Table 1 Baseline characteristics of the study population.
Characteristics | All patients n = 414 | Survivors n = 367 | Non-survivors n = 47 | p-value |
|---|---|---|---|---|
Age, years | 66.2 ± 12.4 | 65.8 ± 12.3 | 69.4 ± 12.9 | 0.064 |
Male | 238 (57.5) | 210 (57.2) | 28 (59.6) | 0.876 |
Medical history | ||||
Hypertension | 147 (35.5) | 132 (36.0) | 15 (31.9) | 0.631 |
Diabetes mellitus | 106 (25.6) | 90 (24.5) | 16 (34.0) | 0.160 |
Malignancy | 196 (47.3) | 169 (46.0) | 27 (57.4) | 0.163 |
Source of infection | ||||
Pulmonary | 105 (25.4) | 81 (22.1) | 24 (51.1) | 0.000 |
Genitourinary | 72 (17.4) | 69 (18.8) | 3 (6.4) | 0.039 |
Hepatobiliary | 128 (30.9) | 120 (32.7) | 8 (17.0) | 0.029 |
Others | 15 (3.6) | 13 (3.5) | 2 (4.3) | 0.683 |
Laboratory findings | ||||
White blood cell, × 103/uL | 9.0 [5.3–14.8] | 8.8 [5.3–14.3] | 11.3 [5.9–17.7] | 0.143 |
Hemoglobin, g/dL | 11.0 [9.5–12.7] | 11.0 [9.7–12.7] | 11.3 [8.9–13.3] | 0.902 |
Creatinine, mg/dL | 1.2 [0.9–1.8] | 1.2 [0.9–1.7] | 1.3 [0.8–2.2] | 0.567 |
Albumin, g/dL | 2.9 [2.4–3.3] | 2.9 [2.5–3.4] | 2.6 [2.2–3.1] | 0.010 |
Total bilirubin, mg/dL | 0.9 [0.6–1.7] | 0.9 [0.6–1.7] | 0.8 [0.5–1.8] | 0.126 |
CRP, mg/dL | 7.7 [3.8–18.3] | 7.5 [3.7–18.3] | 9.0 [4.3–19.3] | 0.361 |
Initial Lactate, mmol/L | 2.5 [1.7–4.5] | 2.3 [1.7–4.2] | 4.1 [2.2–7.0] | 0.000 |
Initial SOFA score | 5.0 [3.0–6.0] | 4.0 [3.0–6.0] | 5.0 [4.0–7.0] | 0.008 |
APACHE II score | 14 [10–19] | 14 [10–19] | 20 [14–25] | 0.000 |