Figure 2
Flow cytometric analysis of intraplatelet P-VASP (a) before clopidogrel therapy and (b) after clopidogrel therapy in the presence of PGE1, ADP stimulation, or a combination of PGE1 and ADP. Note there was a significant difference between the mean fluorescence intensity (MFI) with PGE1 and PGE1 in the presence of ADP stimulation before clopidogrel therapy, but no significant difference was found after clopidogrel therapy. (c) Platelet reactivity index (PRI) was calculated and compared before (pre) and after (post) clopidogrel therapy. The horizontal line represents the median, the box the 25th and 75th percentile, the whiskers the 1.5 times interquartile range, and the points outside the whiskers are outliers. *P < 0.0001.
