Figure 4

Co-occurrence networks of gut bacteria identified in metagenomics analyses of 283 middle-aged adults and their relationships with adiposity measures and metabolic traits. (a) Co-occurrence networks of species (MGSs) in communities associated with adiposity measures and metabolic phenotypes. Node size reflects mean abundance of species across samples (see Supplementary Dataset 2). Node colors corresponds to the community attribution. Blue and red color edges represent positive and inverse correlation coefficients respectively. Thickness of an edge is proportional to the absolute value of the correlation coefficient (see Methods and Supplementary Dataset 2 for exact value). (b) Microbial community content: mean abundance across all samples (left panel); number of species in each community (middle panel); and the relative abundance of genera in the communities is given in the right panel.