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Figure 1

From: Ibrutinib does not prevent kidney fibrosis following acute and chronic injury

Figure 1

Ibrutinib promotes renal fibrosis after unilateral ureteric obstruction (UUO). (A) Design of the study. (B–E) Representatives images and quantifications of Fibronectin (B), Sirius Red (C), B220 (D) and F4/80 (E) staining in sham and UUO mice receiving ibrutinib (Ibru) or vehicle (Veh). Data are represented as means ± SEM. *p < 0.05 (Mann–Whitney test; n = 6 mice per group); ns, not significant.

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