Figure 2

Overview of the anthrax toxin translocation complex. CryoEM density map (A) side and (B) top view of LFN translocating through PApore. Inset: folded LFN model density (PDB 6PSN) compared to translocating LFN density. Molecular model (C) side and (D) top view of LFN translocating through PApore. Inset: folded LFN model (PDB 6PSN) compared to translocating LFN model. Discontinuous density indicated in model with dashed magenta lines.