Figure 2 | Scientific Reports

Figure 2

From: Cord blood DNA methylation modifications in infants are associated with white matter microstructure in the context of prenatal maternal depression and anxiety

Figure 2

Cord blood DNA methylation levels associated with infant WM microstructure-related changes (νIC) showing a sex-by-prenatal maternal depression and anxiety symptom interaction. (A) Circos plot depicts genomic distribution of differentially methylated positions (DMPs) across the human genome. (Outer ring) Each chromosome is shown as a different color and the relative chromosome size is represented by the bar length. (Inner rings) Represent the relative location of DMPs across all chromosomes in the full dataset (black), females only (orange), and males only (blue). Sex chromosomes were omitted from the analysis. B) Pie chart showing the percent distribution of DMPs to standard genomic features. 5′UTR = 5′ untranslated region’ 3′UTR = 3′ untranslated region; TSS = transcription start site; TSS200 = 0–200 bp upstream of TSS; TSS1500 = 200–1500 bp upstream of TSS. Circos plot and pie chart were generated using the R environment44.

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