Figure 5
From: Feasibility study on stereotactic radiotherapy for total pulmonary vein isolation in a canine model
Histologic changes after irradiation observed at 4 months. A visually definite transmural necrotic lesion is observed on the irradiated area at 4 months. Compared to the normal atrial myocardium near the irradiated lesion (a), irradiated atrial myocardium (b) shows massive hemorrhage with anucleated wavy fibers with extensive interstitial fibrosis. H&E hematoxylin and eosin, MT Masson’s trichrome.
