Figure 3 | Scientific Reports

Figure 3

From: Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption

Figure 3

SPR/EIS of P1 and P3 with or without Cu2+. The black curves are the SPR responses, and the blue curves are the calculated bilayer resistance values from EIS measurements. Peptides were added in small increments on top of a stable POPC tBLM. SPR/EIS signals were collected simultaneously as a function of time: (A) P1, (B) P3, (C) P1-Cu2+, and (D) P3-Cu2+. The peptides were metallated using a 1:1 stoichiometric amount of CuCl2. See also Fig. S3. (µM = µmol/L).

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