Table 2 Rheumatological clinical and imaging features according to Whipple disease entity.

From: Rheumatological features of Whipple disease

 

CWD

N = 11

LWD

N = 24

AWD

N = 15

PAWD

N = 18

Total

N = 68

Clinical features n/N (%)

Exclusive peripheral involvement

6/11 (55)

15/24 (63)

9/15 (60)

12/18 (67)

42/68 (62)

Axial +/− peripheral involvement

5/11 (45)

9/24 (38)

6/15 (40)

6/18 (33)

26/68 (38)

Arthritis

10/11 (91)

22/24 (92)

13/15 (87)

15/18 (83)

60/68 (88)

Inflammatory arthralgia

11/11 (100)

21/24 (88)

12/15 (80)

18/18 (100)

62/68 (91)

Monoarticular involvement

1/7 (14)

2/22 (9.1)

0/10 (0)

1/13 (7.7)

4/52 (7.7)

Oligoarticular involvement

3/7 (43)

12/22 (55)

3/10 (30)

7/13 (54)

25/52 (48)

Polyarticular involvement

3/7 (43)

8/22 (36)

7/10 (70)

5/13 (38)

23/52 (44)

Symmetric

3/8 (38)

8/20 (40)

4/8 (50)

5/9 (56)

20/45 (44)

Intermittent

4/8 (50)

19/21 (90)

11/12 (92)

8/12 (67)

42/53 (79)

Inflammatory back pain

5/11 (45)

8/24 (33)

5/14 (36)

7/18 (39)

25/67 (37)

Imaging features n/N (%)

Radiographic joint space narrowing

4/7 (57)

4/13 (31)

4/8 (50)

4/13 (31)

16/41 (39)

Radiographic erosions

4/10 (40)

4/21 (19)

1/10 (10)

1/15 (6.7)

10/56 (18)

Radiographic destruction

2/10 (20)

2/19 (11)

2/10 (20)

0/14 (0)

6/53 (11)

Spondylodiscitis on MRI

0/0 (0)

2/8 (25)

1/3 (33)

0/2 (0)

3/13 (23)

Sacroiliitis on CT and/or MRI

2/3 (67)

1/5 (20)

3/4 (75)

1/3 (33)

7/15 (47)

  1. AWD arthropathic Whipple disease; CT computed tomography; CWD classic Whipple disease; LWD localized Whipple disease; MRI magnetic resonance imaging; PAWD probably arthropathic Whipple disease.