Table 4 Diagnostic performance of commonly reported symptoms.
From: Cross sectional study of the clinical characteristics of French primary care patients with COVID-19
Symptom | Sensitivity, % (95%CI) | Specificity, % (95%CI) | ROC area (95%CI) | Positive predictive value, % (95%CI) | Negative predictive value, % (95%CI) |
|---|---|---|---|---|---|
ENT symptoms | |||||
Dry throat (n = 1476) | 42.1 (35.9–48.4) | 58.7 (55.8–61.4) | 0.50 (0.47–0.54) | 17.3 (14.4–20.6) | 83.1 (80.4–85.5) |
Dry nose (n = 1475) | 26.6 (21.2–32.5) | 81.6 (79.3–83.7) | 0.54 (0.51–0.57) | 22.9 (18.2–28.2) | 84.4 (82.2–86.4) |
Sore throat (n = 1517) | 4.0 (1.9–7.2) | 92.3 (90.7–93.7) | 0.48 (0.47–0.50) | 9.4 (4.6–16.5) | 82.9 (80.8–84.8) |
Stuffy nose (n = 1477) | 23.4 (18.3–29.1) | 66.5 (63.8–69.2) | 0.45 (0.42–0.48) | 12.6 (9.7–15.9) | 80.9 (78.3–83.2) |
Loss of taste (n = 1543) | 31.2 (25.6–37.3) | 94.5 (93.1–95.7) | 0.63 (0.60–0.66) | 52.7 (44.4–60.9) | 87.5 (85.7–89.2) |
Loss of smell (n = 1543) | 35.6 (29.7–41.8) | 93.0 (91.5–94.4) | 0.64 (0.61–0.67) | 50.0 (42.5–57.5) | 88.0 (86.2–89.7) |
Loss of taste and smell (n = 1543) | 22.1 (17.2–27.8) | 96.7 (95.6–97.6) | 0.59 (0.57–0.62) | 57.1 (46.7–67.1) | 86.4 (84.5–88.1) |
Loss of taste or smell (n = 1543) | 44.7 (38.4–51.0) | 90.8 (89.1–92.3) | 0.68 (0.65–0.71) | 48.7 (42.1–55.3) | 89.3 (87.5–90.9) |
Other symptoms | |||||
Chest pain (n = 1478) | 17.1 (12.6–22.3) | 78.5 (76.1–80.7) | 0.48 (0.45–0.50) | 14.0 (10.3–18.4) | 82.2 (79.8–84.3) |
Fever (n = 1497) | 57.5 (51.2–63.7) | 55.3 (52.5–58.1) | 0.56 (0.53–0.60) | 20.7 (17.7–23.9) | 86.6 (84.0–88.9) |
Fatigue (n = 1517) | 13.1 (9.2–18.0) | 83.1 (80.9–85.1) | 0.48 (0.46–0.51) | 13.4 (9.4–18.2) | 82.8 (80.6–84.9) |
Headache (n = 1487) | 45.2 (39.0–51.6) | 47.1 (44.3–50.0) | 0.46 (0.43–0.50) | 14.9 (12.4–17.6) | 80.8 (77,8–83.6) |
Cough (n = 1517) | 51.8 (45.4–58.1) | 55.5 (52.7–58.3) | 0.54 (0.50–0.57) | 18.8 (15.9–21.9) | 85.3 (82.7–87.7) |
Muscle pain (n = 1517) | 25.5 (20.2–31.4) | 83.6 (81.5–85.6) | 0.55 (0.52–0.58) | 23.6 (18.7–29.1) | 85.0 (82.9–86.9) |
Dyspnea (n = 1517) | 9.2 (5.9–13.4) | 84.2 (82.1–86.2) | 0.47 (0.45–0.49) | 10.3 (6.7–15.1) | 82.4 (80.2–84.4) |
Diarrhea (n = 1480) | 19.0 (14.4–24.4) | 70.8 (68.2–73.4) | 0.45 (0.42–0.48) | 11.8 (8.9–15.4) | 81.0 (78.5–83.3) |
