Table 1 Anterior latissimus dorsi fiber size and cellular parameters in control and mesterolone-treated groups.

From: Differential response of oxidative and glycolytic skeletal muscle fibers to mesterolone

Parameter

Control

M1

M2

M3

M4

Fiber CSA (µm2)

1817 ± 319

2047 ± 323

1836 ± 156

2127 ± 245

2038 ± 526

Lesser fiber diameter (µm)

37.32 ± 4.11

39.82 ± 3.16

37.94 ± 1.83

40.17 ± 2.32

39.26 ± 5.44

SCs per 100 fibers

22.8 ± 3.6

42.5 ± 7.0**

35.3 ± 6.5*

44.3 ± 7.6**

35.5 ± 4.9**

SCs per 1 mm

10.8 ± 1.7

21.0 ± 3.5**

17.9 ± 3.3**

21.1 ± 3.6**

17.7 ± 2.5**

SC frequency (%)

5.9 ± 0.5

9.4 ± 2.4**

9.1 ± 1.7*

8.6 ± 1.6*

8.8 ± 1.6*

Surface area of plasma- lemma per SC (µm2)

10,938 ± 632

6044 ± 912**

6851 ± 1331**

6054 ± 745**

7031 ± 1068**

MN per 100 fibers

363.3 ± 65.0

418.8 ± 78.9

353.8 ± 20.8

477.0 ± 75.0

369.5 ± 42.0

MN per 1 mm

171.5 ± 30.5

208.7 ± 39.3

170 ± 10

223.3 ± 35.2

176.2 ± 20

MND (µm3)

10,634 ± 1234

9926 ± 1591

10,830 ± 1135

9619 ± 1042

11,454 ± 1969

  1. M1, M2, M3, M4: groups treated with 4, 8, 12, and 16 mg/kg mesterolone, respectively. CSA: cross-sectional area; SC: satellite cell; MN: myonuclei; MND: myonuclear domain. Values represent the means ± standard deviations. *P < 0.05, **P < 0.01 significantly different from the control group (ANOVA, LSD post-hoc).
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