Table 1 Demographics and baseline characteristics of COVID-19 patients and controls.

From: Cytokine signatures of end organ injury in COVID-19

Characteristic

Controls

N = 51

COVID-19

N = 90

p-value

Demographics

Age (median, IQR)

64 (57, 78)

66 (57, 77)

0.5

Sex, female (n, %)

28 (55%)

33 (37%)

0.054

Race (n, %)

  

< 0.001

Asian

3 (5.9%)

6 (7.5%)

 

Black

8 (16%)

12 (15%)

 

Other

3 (5.9%)

18 (22%)

 

White

29 (57%)

44 (55%)

 

BMI (median, IQR)

25.2 (21.7, 28.8)

27.6 (23.2, 31·1)

0.030

Smoking status (n, %)

  

0.029

Active smoker

4 (8.0%)

0 (0%)

 

Former smoker

14 (28%)

30 (33%)

 

Never smoker

32 (64%)

60 (67%)

 

Comorbidities (n, %)

CAD

12 (24%)

13 (14%)

0.3

DM

9 (18%)

28 (31%)

0.12

HTN

27 (53%)

51 (57%)

0.8

CVA

9 (18%)

9 (10%)

0.3

CKD/ESRD

6 (12%)

9 (10%)

> 0.9

Cirrhosis

1 (2.0%)

1 (1.1%)

> 0.9

COPD

7 (14%)

6 (6.7%)

0.2

Asthma

6 (12%)

10 (11%)

> 0.9

Active cancer

19 (37%)

11 (12%)

0.001

Immunosuppressed statea

18 (35%)

4 (4.4%)

< 0.001

Home medications (n, %)

Immunosuppressive medications (past 30 days)

16 (31%)

15 (17%)

0.070

ACE/ARBs

13 (25%)

25 (28%)

> 0.9

Statins

22 (43%)

33 (37%)

0.6

NSAIDs

16 (31%)

24 (27%)

0.7

PPIs

15 (29%)

21 (23%)

0.6

Day 1 vital signs (median, IQR)

Highest temperature (°C)

37.00 (36.75, 37.70)

38.30 (37.50, 39.00)

< 0.001

Highest heart rate

95 (86, 110)

100 (91, 105)

0.2

Highest respiratory rate

20.0 (18.0, 22.0)

22.0 (20.0, 30.0)

< 0.001

Lowest systolic blood pressure

106 (100, 118)

105 (92, 113)

0.2

  1. BMI Body Mass Index, CAD coronary artery disease, DM diabetes mellitus, HTN hypertension, CVA cerebrovascular accident, CKD/ESRD chronic kidney disease/end stage renal disease, COPD chronic obstructive pulmonary disease, ACE/ARBs angiotensin-converting enzyme inhibitors/angiotensin-II receptor blockers, NSAIDs nonsteroidal anti-inflammatory drugs, PPIs proton pump inhibitors.
  2. aChemotherapy or radiotherapy within last 6 months; inherited immunodeficiency.