Figure 7
From: Immune modulation via adipose derived Mesenchymal Stem cells is driven by donor sex in vitro
Assessment of fMSC and fPBMC whilst blocking the activity of IDO1 with (EPA) (a) effects of EPA on suppression PBMC (% suppression), (b) EPA effects on MSC mediated PBMC mean fluorescence intensity (MFI) and (c) effect of MSC IDO1 secretion by adding EPA to a co-culture. (d) Mean IDO1 secretion (n = 8) can be correlated (R2 = 0.77) to MSC mediated immune suppression (n = 8) and can be predicted by the equation (+) = added to culure, (−) = not added to culture.
