Figure 1 | Scientific Reports

Figure 1

From: Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

Figure 1

Association of the adipogenesis score with expression of adipogenesis- and adipocyte-related genes, and correlation with adipocyte score in the GSE96058 and TCGA cohorts. Boxplots comparing low and high adipogenesis score tumors of gene expression levels of (A) adipogenesis-related genes; Acetyl-CoA carboxylase/ACLY, ATP citrate lyase/ACACA, NADP-dependent malic enzyme/SLC25A10, and mitochondrial dicarboxylate carrier/ME1, and (B) adipocyte-related genes; adiponectin/ADIPOQ, leptin/LEP, lipoprotein/LPL, and perilipin 1/PLIN1 in breast cancer. P-value was calculated using Mann–Whitney U test. (C) Correlation pots between adipogenesis and adipocytes scores. Spearman correlation coefficient (r) was used to the analysis.

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