Table 3 Mahalanobis distances of the four model species to humans for all genes combined under healthy, transiently and constantly inflamed conditions as well as for the different functional gene groups: tenogenic markers, collagens, MMPS and inflammatory mediators.
Mouse | Rat | Sheep | Horse | |
|---|---|---|---|---|
Mahalanobis distances all genes per condition | ||||
Healthy | 20.01 | 27.44 | 24.78 | 23.05 |
Transient Inflammation | 13.49 | 18.66 | 10.62 | 9.59 |
Constant Inflammation | 10.50 | 17.45 | 8.94 | 12.97 |
Mahalanobis distances all conditions per group of genes | ||||
SCX, TNC, TNMD | 5.45 | 12.21 | 10.54 | 6.88 |
COL1, COL3, COL5 | 8.28 | 13.73 | 12.88 | 8.45 |
MMP1, MMP3, MMP13 | 8.53 | 11.27 | 8.60 | 4.65 |
COX2, IL6, | 15.82 | 14.25 | 18.51 | 17.77 |
