Table 1 Characteristics of NET cases tested.
Utah cancer registry cases excluding those tested | Cases tested | Molecular classification by copy number variation (CNV) | |||
|---|---|---|---|---|---|
18LOH | NoCNV | MultiCNV | |||
Number of cases | 516 | 47 | 19 | 20 | 8 |
Diagnosis years | 1999–2014 | 1999–2018 | 1999–2016 | 2003–2018 | 2011–2018 |
Race Caucasian | 500 (97%) | 44 (94%) | 18 (94%) | 18 (90%) | 8 (100%) |
Male | 285 (55%) | 28 (60%) | 10 (52%) | 12 (60%) | 6 (75%) |
Average age at diagnosis (range) | 62.1 (19–90) | 60.6 (25–87) | 59.8 (44–87) | 59.2 (25–77) | 66.0 (50–85) |
Tumor location [ICD-O-3 site codes] | |||||
Small intestine [170–173, 178, 179] | 475 (92%) | 44 (94%) | 19 (100%) | 17 (85%) | 8 (100%) |
Appendix [181] | 41 (8%) | 3 (6%) | 0 | 3 | 0 |
Stage [SEER summary stage] | |||||
Localized [1] | 170 (33%) | 12 (26%) | 1 (5%) | 8 (40%) | 3 (38%) |
Regional [2, 3, 4] | 224 (43%) | 23 (49%) | 11 (58%) | 9 (45%) | 3 (38%) |
Distant [7] | 110 (21%) | 12 (26%) | 7 (37%) | 3 (15%) | 2 (25%) |
Unknown [9] | 12 (2%) | 0 | 0 | 0 | 0 |
Grade | |||||
Total tumors graded | 224 (43%) | 37 (79%) | 17 (89%) | 12 (60%) | 8 (100%) |
Grade 1 | 155 (69%) | 26 (70%) | 12 (71%) | 9 (70%) | 5 (63%) |
Grade 2 | 59 (26%) | 10 (27%) | 5 (29%) | 3 (25%) | 2 (25%) |
Grade 3 | 10 (4%) | 1 (3%) | 0 | 0 | 1 (13%) |
Unknown grade | 292 (57%) | 10 (21%) | 2 (11%) | 8 (40%) | 0 |
Tobacco use indication | 159 (31%) | 13 (28%) | 7 (37%) | 4 (20%) | 2 (25%) |
Family history of small intestinal NET | 14 (3%) | 1 (2%) | 1 (5%) | 0 | 0 |
