Figure 4
Heatmap of differentially expressed genes (DEGs) in the hypothalamus of bunting exhibiting photosensitive and photorefractory states (rows) at hours 10 (a), hour 14 (b) and hour 18 (c) and hour 22 (column) (d) (n = 2/time point/state except at hour 22 in the photorefractory state in which n = 1). Log-transformed values were normalized and plotted as z-scores (blue, minimum; red, maximum). A blue continuous line running through the heatmap shows expression differences from mean value (dashed line). Genes with similar expression patterns have been clustered together. Underneath each heatmap, the results of significantly enriched pathways (padj. < 0.05), and STRING DEG network analysis in which the nodes/circles represent gene-encoded proteins, while the edge/lines connecting circles represent the protein–protein interactions. The empty nodes represent proteins of an unknown 3D structure, while the filled nodes represent the known or a predicted 3D structure.
