Figure 4

The IST heterogeneity results in the human data set, including healthy and COPD phenotypes (GOLD 1–4). Panels (a) and (b) show % of measured values over the predicted values for age in different lung conditions. Kruskal–Wallis test was applied for multiple groups comparison with abnormal distribution. Panel (c) shows the confusion matrix result of the logistic regression analysis in percentage. This analysis grouped patients by the IST heterogeneity indices and compared them with the classification results using Spirometry (standard method). *p < 0.05.