Table 1 Baseline characteristics of ACLF patients with and without sarcopenia.
Variables | All patients (n = 171) | Sarcopenia (n = 95) | No sarcopenia (n = 76) | P value |
|---|---|---|---|---|
Age, yr, SD | 44.5 ± 10.8 | 44.7 ± 10.7 | 44.3 ± 11.0 | 0.801 |
Sex, male, n (%) | 146 (85.4) | 78 (82.1) | 68 (89.5) | 0.175 |
BMI, kg/m2, SD | 22.6 ± 4.0 | 20.9 ± 2.9 | 24.8 ± 4.2 | < 0.001 |
< 24.0 (non-obese), n (%) | 118 (69.0) | 81 (85.3) | 37 (48.7) | < 0.001 |
≥ 24.0 (obese), n (%) | 53 (31.0) | 14 (14.7) | 39 (51.3) | |
Liver cirrhosis, n (%) | 108 (63.2) | 72 (75.8) | 36(47.4) | < 0.001 |
Etiology of liver disease, n (%) | 0.417 | |||
Hepatitis B virus | 115 (67.3) | 62 (65.3) | 53 (69.7) | |
Alcohol | 29 (17) | 18 (18.9) | 11 (14.5) | |
Hepatitis B virus and alcohol | 16 (9.4) | 7 (7.4) | 9 (11.8) | |
Other | 11 (6.4) | 8 (8.4) | 3 (3.9) | |
Hepatic encephalopathy, n (%) | 40 (23.4) | 22 (23.2) | 18 (23.7) | 0.936 |
Ascites, n (%) | 133 (77.8) | 78 (82.1) | 55 (72.4) | 0.128 |
MELD score, IQR | 22.4 ± 6.3 | 21.8 ± 6.5 | 23.1 ± 6.1 | 0.208 |
Serum sodium, mmol/L, SD | 134.5 ± 4.7 | 133.6 ± 4.6 | 135.5 ± 4.5 | 0.009 |
Serum creatinine, μmol/L, IQR | 60.0 (48.0–71.7) | 64.5 (53.1–76.9) | 55.5 (47.2–69.7) | 0.009 |
Serum bilirubin, mg/dL, IQR | 20.9 (12.5–27.5) | 23.5 (15.1–30.2) | 18.3 (11.0–23.9) | 0.007 |
Serum albumin, g/L, SD | 29.9 ± 5.6 | 29.4 ± 5.3 | 30.4 ± 5.9 | 0.241 |
INR, IQR | 2.4 (2.1–3.0) | 2.4 (2.0–2.9) | 2.3 (2.1–3.2) | 0.876 |
Platelets, ×109/L, IQR | 96 (66–141.8) | 55.5 (47.2–69.7) | 100.5 (64.5–150.8) | 0.618 |
L3-SMI, cm2/m2, SD | 41.2 ± 8.3 | 35.4 ± 4.7 | 48.4 ± 5.9 | < 0.001 |
