Table 3 Features associated with mortality by Cox regression analysis in patients with ACLF.

From: Use of skeletal muscle index as a predictor of short-term mortality in patients with acute-on-chronic liver failure

Variables

Univariate

Multivariate

HR (95% CI)

P value

HR (95% CI)

P value

Age, per yr

1.022 (0.998–1.046)

0.076

  

Male sex

0.897 (0.425–1.895)

0.776

  

Obesity (≥ 24.0 kg/m2)

0.784 (0.435–1.415)

0.420

  

Liver cirrhosis

2.175 (1.171–4.039)

0.014

2.758 (1.323–5.750)

0.007

Hepatic encephalopathy

0.809 (0.611–1.069)

0.136

  

Ascites

1.933 (0.915–4.082)

0.084

  

MELD score

1.104 (1.054–1.157)

 < 0.001

  

Serum sodium, per mmol/L

0.943 (0.895–0.993)

0.026

  

Serum creatinine, per μmol/L

1.003 (0.996–1.010)

0.439

  

Serum bilirubin, per mg/dL

1.047 (1.026–1.069)

 < 0.001

1.049 (1.026–1.073)

 < 0.001

Serum albumin, per g/L

0.996 (0.951–1.042)

0.851

  

INR, per unit

1.922 (1.418–2.605)

 < 0.001

1.725 (1.263–2.355)

0.001

Platelet

0.996 (0.991–1.000)

0.064

  

L3-SMI, per cm2/m2

1.008 (0.977–1.039)

0.630

  

Sarcopenia

1.054 (0.623–1.783)

0.845

  
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