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Figure 1

From: Association between alterations in plasma metabolome profiles and laminitis in intensively finished Holstein bulls in a randomized controlled study

Figure 1

Exploratory data analysis. (a) Principal component analyses (PCA) of the combined data set of blood metabolome, body weight, insulin concentration, laminitis score, heel horn erosion and interdigital dermatitis score. Group fed low energy and protein diet (LEP): baseline n = 11, slaughter n = 15. Group fed high energy and protein diet (HEP): baseline n = 13, slaughter n = 15. Each dot represents the data of one bull at one sampling day. (b) Scores plot of sparse partial least squares-discriminant analysis (sPLS-DA) between components 1 and 2 applied to the dataset only at slaughter, n = 15 (blood metabolome, blood biochemistry, insulin concentration, body weight, laminitis score, heel horn erosion and interdigital dermatitis score). (c) Loadings of component 1 calculated by sPLS-DA of the dataset at slaughter. The variables listed on the left were ranked by the absolute values of their loadings, the color scheme on the right shows relative differences of the compounds between the feeding groups at slaughter. PC x:y = Phosphatidylcholine with total length of x carbon atoms and y unsaturated bonds in its acyl chains, aa = diacyl, ae = acyl-alkyl.

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