Figure 5 | Scientific Reports

Figure 5

From: Remodeling of bronchial epithelium caused by asthmatic inflammation affects its response to rhinovirus infection

Figure 5

Airway epithelial responses to HRV infection are not impaired in asthma. (a) Similar replication of HRV16 in ALI-grown mucociliary epithelium from asthma patients with eosinophilic (E), neutrophilic (N), pauci-granulocytic (P) or mixed inflammatory (Mix) phenotypes. Data are presented as medians and range (n = 40; no difference with Kruskal–Wallis test). (b) HRV-related changes (log2fold data shown) in the expression of viral response genes were similar in cells from asthma patients and normal subjects (left panel), and in comparison of asthma patients with E and N inflammation in the lower airways (right panel).

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