Table 1 Baseline clinicopathological characteristics associated with peritumoral edema.

From: Peritumoral edema in breast cancer at preoperative MRI: an interpretative study with histopathological review toward understanding tumor microenvironment

Characteristics

All patients

Patients without peritumoral edema

(n = 102)

Patients with peritumoral edema

(n = 34)

P value

Age*, years

49.2 (8.9)

47.7 (8.2)

53.7 (9.4)

< 0.001a

T stage

< 0.001b

T1

86 (63.2)

80 (78.4)

6 (17.6)

 

T2

47 (34.6)

20 (19.6)

27 (79.4)

 

T3

3 (2.2)

2 (2.0)

1 (2.9)

 

N stage

0.004b

N0

98 (72.1)

79 (77.5)

19 (55.9)

 

N1

29 (21.3)

19 (18.6)

10 (29.4)

 

N2

8 (5.9)

4 (3.9)

4 (11.8)

 

N3

1 (0.7)

0 (0.0)

1 (2.9)

 

Histologic type

0.83c

Ductal

125 (91.9)

94 (92.2)

31 (91.2)

 

Lobular

4 (2.9)

3 (2.9)

1 (2.9)

 

Others**

7 (5.1)

5 (4.9)

2 (5.9)

 

Histologic grade

< 0.001b

Low

20 (14.7)

20 (19.6)

0 (0.0)

 

Moderate

99 (72.8)

76 (74.5)

23 (67.6)

 

High

17 (12.5)

6 (5.9)

11 (32.4)

 

HR status

0.04c

Negative

26 (19.1)

15 (14.7)

11 (32.4)

 

Positive

110 (80.9)

87 (85.3)

23 (67.6)

 

HER2 status

0.05c

Negative

106 (77.9)

84 (82.4)

22 (64.7)

 

Positive

30 (22.1)

18 (17.6)

12 (35.3)

 

Ki-67 index

< 0.001c

< 14%

68 (50.0)

62 (60.8)

6 (17.6)

 

≥ 14%

68 (50.0)

40 (39.2)

28 (82.4)

 

Subtype

< 0.001c

Luminal A

56 (41.2)

52 (51.0)

4 (11.8)

 

Luminal B

54 (39.7)

35 (34.3)

19 (55.9)

 

Triple-negative

14 (10.3)

9 (8.8)

5 (14.7)

 

HER2-enriched

12 (8.8)

6 (5.9)

6 (17.6)

 
  1. Unless otherwise indicated, data are presented as numbers of patients, with percentages in parentheses.
  2. *Data are presented as mean values, with standard deviation in parentheses.
  3. HR hormone receptor, HER2 human epidermal growth factor receptor 2.
  4. **Others include mucinous (n = 4) and metaplastic (n = 3) carcinomas.
  5. aIndependent t test, bChi-squared test for trend, cChi-squared test.
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