Table 1 Comparison between the most prevalent rodent stroke models and the model in the current study.

From: A novel model of ischemia in rats with middle cerebral artery occlusion using a microcatheter and zirconia ball under fluoroscopy

 

Suture model3,4

Thromboembolic model19

Macrosphere model14,15

Current model

Procedure

Incision

Incision

Incision

Puncture

Approach site

Neck

Neck

Neck

Tail

Affected ischemic area

MCA/ECA/AChA/VTA/HTA/PCA

MCA/ECA

MCA/ECA/AChA

MCA

Identify the vessel occlusion while creating the model

Impossible

Impossible

Impossible

Possible

Identify model success while creating the model

Impossible

Impossible

Impossible

Possible

Model failure rate

2/12 (17%)14

6/26 (23%)19

3/13 (23%)14

2/10 (20%)

24-h mortality

1/10 (10%)14

1/26 (4%)19

1/10 (10%)14

0/10 (0%)

SAH rate

8–30%14,16,17,18

4/26 (15%)19

0/13 (0%)14

0/10 (0%)

Reperfusion stroke model

Possible

Possible

Impossible

Impossible

  1. AChA anterior choroidal artery, ECA external carotid artery, HTA hypothalamic artery, MCA middle cerebral artery, PCA posterior cerebral artery, SAH subarachnoid hemorrhage, VTA ventral thalamic artery.
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