Table 2 Univariate analysis of locoregional recurrence by clinicopathologic features throughout the overall cohort.
From: Perineural invasion as a risk factor for locoregional recurrence of invasive breast cancer
Characteristic | HR (95% CI) | p-value |
|---|---|---|
Presence of PNI | 1.39 (1.08–1.78) | 0.01 |
Age (per year) | 0.98 (0.97–0.99) | 0.001 |
Tumor size (per cm) | 1.05 (1–1.1) | 0.073 |
Lymph nodes involved (per node) | 1 (0.98–1.02) | 0.92 |
ER-negative | 1.83 (1.49–2.24) | < 0.001 |
PR-negative | 1.44 (1.19–1.75) | < 0.001 |
HER2+ | 1.04 (0.81–1.34) | 0.754 |
High histologic grade | 1.45 (1.16–1.8) | 0.001 |
Lymphovascular invasion | 1.33 (1.1–1.61) | 0.003 |
Lumpectomy (vs mastectomy) | 0.39 (0.32–0.48) | < 0.001 |
Laterality (right vs left) | 0.87 (0.72–1.05) | 0.14 |
Margins (vs negative) | 0.003 | |
< 2 mm | 1.73 (1.11–2.68) | |
Positive | 1.61 (1.11–2.33) | |
Chemotherapy administered | 1.36 (1.07–1.74) | 0.014 |
Radiotherapy administered | 1.17 (0.97–1.42) | 0.098 |
