Table 4 Clinicopathologic characteristics of patients with PNI and matched PNI-negative controls.
From: Perineural invasion as a risk factor for locoregional recurrence of invasive breast cancer
Characteristic | 0, N = 1320a | 1, N = 1320a | p-valueb |
|---|---|---|---|
Age | 58 (50, 64) | 56 (48, 65) | 0.6 |
Tumor size | 1.70 (1.10, 2.50) | 1.90 (1.30, 2.60) | < 0.001 |
LNs | 0.0 (0.0, 2.0) | 0.0 (0.0, 2.0) | 0.6 |
ER | 0.5 | ||
Positive | 1195 (91%) | 1205 (91%) | |
Negative | 125 (9.5%) | 115 (8.7%) | |
PR | 0.8 | ||
Positive | 1101 (83%) | 1106 (84%) | |
Negative | 219 (17%) | 214 (16%) | |
HER2 | 0.9 | ||
Negative | 1202 (91%) | 1205 (91%) | |
Positive | 118 (8.9%) | 115 (8.7%) | |
Histologic grade | 0.4 | ||
1–2 | 281 (21%) | 299 (23%) | |
3 | 1039 (79%) | 1021 (77%) | |
LVI | 0.4 | ||
Negative | 647 (49%) | 626 (47%) | |
Positive | 673 (51%) | 694 (53%) | |
Surgery | 0.3 | ||
Mastectomy | 576 (44%) | 546 (41%) | |
Partial mastectomy | 744 (56%) | 774 (59%) | |
Side | > 0.9 | ||
Left | 667 (51%) | 664 (50%) | |
Right | 653 (49%) | 656 (50%) | |
Chemo | 897 (68%) | 877 (66%) | 0.4 |
Radiation | 873 (66%) | 886 (67%) | 0.6 |