Table 4 Clinicopathologic characteristics of patients with PNI and matched PNI-negative controls.

From: Perineural invasion as a risk factor for locoregional recurrence of invasive breast cancer

Characteristic

0, N = 1320a

1, N = 1320a

p-valueb

Age

58 (50, 64)

56 (48, 65)

0.6

Tumor size

1.70 (1.10, 2.50)

1.90 (1.30, 2.60)

< 0.001

LNs

0.0 (0.0, 2.0)

0.0 (0.0, 2.0)

0.6

ER

  

0.5

Positive

1195 (91%)

1205 (91%)

 

Negative

125 (9.5%)

115 (8.7%)

 

PR

  

0.8

Positive

1101 (83%)

1106 (84%)

 

Negative

219 (17%)

214 (16%)

 

HER2

  

0.9

Negative

1202 (91%)

1205 (91%)

 

Positive

118 (8.9%)

115 (8.7%)

 

Histologic grade

  

0.4

1–2

281 (21%)

299 (23%)

 

3

1039 (79%)

1021 (77%)

 

LVI

  

0.4

Negative

647 (49%)

626 (47%)

 

Positive

673 (51%)

694 (53%)

 

Surgery

  

0.3

Mastectomy

576 (44%)

546 (41%)

 

Partial mastectomy

744 (56%)

774 (59%)

 

Side

  

> 0.9

Left

667 (51%)

664 (50%)

 

Right

653 (49%)

656 (50%)

 

Chemo

897 (68%)

877 (66%)

0.4

Radiation

873 (66%)

886 (67%)

0.6

  1. aStatistics presented: median (IQR); n (%).
  2. bStatistical tests performed: Wilcoxon rank-sum test; chi-square test of independence.