Figure 4 | Scientific Reports

Figure 4

From: High fructose and streptozotocin induced diabetic impairments are mitigated by Indirubin-3-hydrazone via downregulation of PKR pathway in Wistar rats

Figure 4

IHZ attenuates islet damage & fibrosis in pancreatic tissue of diabetic rats by inhibition of oxidative stress. (a) Representative images of histological pancreatic sections incubated with DCFDA to assess oxidative stress (high green fluorescence represents increased ROS generation). (b) Relative fluorescence intensity plotted from (a). (c) Nitrite or nitrate levels measured by Griess assay. (d) Lipid peroxidation levels measured by TBARS assay. Data is presented as mean ± SD of n = 3 animals for each group. ***P < 0.001 vs control group; %P < 0.05, %%%P < 0.001 vs HF + STZ group.

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