Table 4 Obstetrical and neonatal outcomes depending on maternal severity among women with a positive SARS-CoV-2 test.
From: Maternal outcomes and risk factors for COVID-19 severity among pregnant women
Obstetrical/neonatal outcomes | Pregnant women with a positive test result for SARS-CoV-2 | |||
|---|---|---|---|---|
Severe adverse maternal outcomes n = 81 | No/mild adverse maternal outcomes n = 669 | |||
n (%) | 95% CI | n (%) | 95% CI | |
Pregnancy outcomes > 14 WG | ||||
Livebirth | 75 (92.6) | 84.6–97.2 | 656 (98.1) | 96.7–99.0 |
Fetal loss > 14 WG | 6 (7.4) | 2.8–15.4 | 13 (1.9) | 1.0–3.3 |
Termination of pregnancy | 1 (1.2) | 0.0–6.7 | 2 (0.3) | 0.0–1.1 |
Obstetrical outcomes among livebirth | 75 | 656 | ||
GA at delivery (Weeks gestation) | ||||
Median GA (IQR) | 37 (34–38) | 39 (38–40) | ||
Unknown GA at delivery | 0 (0.0) | n.a. | 2 (25.8) | 15.1–41.0 |
Obstetrical management | ||||
All vaginal deliveries | 22 (29.3) | 19.4–41.0 | 447 (68.1) | 64.4–71.7 |
Vaginal delivery after spontaneous onset of labour | 10 (45.5) | 24.4–67.8 | 280 (62.6) | 58.0–67.1 |
Vaginal delivery after induction of labour | 12 (54.5) | 32.2–75.6 | 167 (37.4) | 32.9–42.0 |
Caesarean sections—no (%) | 53 (70.7) | 59.0–80.6 | 203 (30.9) | 27.4–34.6 |
Elective caesarean sections—no (%) | 21 (39.6) | 26.5–54.0 | 85 (41.9) | 35.0–49.0 |
Emergency pre-labor caesarean sections—no (%) | 12 (22.6) | 12.3–36.2 | 16 (7.9) | 4.6–12.5 |
In labour caesarean sections after induction | 12 (22.6) | 12.3–36.2 | 52 (25.6) | 19.8–32.2 |
In labour caesarean sections after spontaneous | 8 (15.1) | 6.7–27.6 | 50 (24.6) | 18.9–31.2 |
Unknown | 0 (0.0) | n.a. | 6 (0.9) | 0.3–2.0 |
Preterm birth among pregnancy with exposure < 37 WG | 51 | 215 | ||
All preterm birth < 37 WG—no (%) | 32 (62.7) | 48.1–75.9 | 78 (36.3) | 29.8–43.1 |
Latrogenic birth among preterm birth—no (%) | 26 (81.3) | 63.6–92.8 | 49 (62.8) | 51.1–73.5 |
Unknown—no (%) | 0 (0.0) | n.a. | 1 (1.3) | 0.0–6.9 |
Unknown GA at delivery | 0 (0.0) | n.a. | 1 (0.5) | 0.1–2.6 |
Preterm birth among pregnancy with exposure < 34WG | 27 | 117 | ||
All preterm birth < 34 WG—no (%) | 14 (51.9) | 31.9–71.3 | 24 (20.5) | 13.6–29.0 |
Latrogenic birth among preterm birth—no (%) | 12 (85.7) | 57.2–98.2 | 14 (58.3) | 36.6–77.9 |
Unknown—no (%) | 0 (0.0) | n.a. | 0 (0.0) | n.a. |
Unknown GA at delivery | 0 (0.0) | n.a. | 1 (0.9) | 0.0–4.7 |
Neonatal outcomes among livebirths | 75 | 656 | ||
Neonatal death | 0 (0.0) | n.a. | 1 (0.2) | 0.0–0.8 |
NICU admission—no (%) | ||||
All NICU admission | 31 (41.3) | 30.1–53.4 | 76 (11.6) | 9.2–14.3 |
Prematurity | 22 (71.0) | 52.0–85.8 | 32 (42.1) | 30.9–54.0 |
Respiratory distress | 15 (48.4) | 30.2–66.9 | 18 (23.7) | 14.7–34.8 |
Sepsis | 0 (0.0) | n.a. | 5 (6.6) | 2.2–14.7 |
Cardiovascular complications | 0 (0.0) | n.a. | 0 (0.0) | n.a. |
Hypoglycemia | 0 (0.0) | n.a. | 10 (13.2) | 6.5–22.9 |
Hyperbilirubinemia | 1 (3.2) | 0.1–16.7 | 9 (11.8) | 5.6–21.3 |
Coagulopathy | 0 (0.0) | n.a. | 0 (0.0) | n.a. |
Neurologic complications | 0 (0.0) | n.a. | 2 (2.6) | 0.3–9.2 |
Other | 3 (9.7) | 2.0–25.8 | 19 (25.0) | 15.7–36.3 |
Unknown | 5 (6.7) | 2.2–14.9 | 47 (7.2) | 5.3–9.4 |
SARS-CoV-2 perinatal transmission rates | ||||
Total of SARS-CoV-2 test at birth—no (%) | 44 (58.7) | 46.7–69.9 | 340 (51.8) | 47.8–55.7 |
Suspected SARS CoV-2 perinatal transmission (positive RT-PCR at birth)—no (%) | 2 (4.5) | 0.6–15.5 | 9 (2.6) | 1.2–5.0 |
Birthweight | ||||
Birthweight < P10—no (%) | 1 (1.3) | 0.0–7.2 | 39 (5.9) | 4.3–8.0 |
Unknown | 5 (6.7) | 2.2–14.9 | 12 (1.8) | 0.9–3.2 |
