Table 1 Demographic characteristics of the women included in the transcriptomics study.
From: The amniotic fluid cell-free transcriptome in spontaneous preterm labor
Time to delivery after amniocentesis ≤ 24 h (n = 10) | Time to delivery after amniocentesis > 24 h (n = 28) | p | |
|---|---|---|---|
Maternal age (years) | 23 (22.2–31.8) | 24.5 (22.8–28) | 0.767 |
Body mass index (kg/m2) | 24.8 (20.9–27.8) | 22.4 (20.2–29.9) | 0.792 |
Nulliparity | 3/10 (30%) | 4/28 (14.3%) | 0.351 |
History of preterm birth | 4/10 (40%) | 10/28 (35.7%) | 1 |
African American ethnicity | 9/10 (90%) | 24/28 (85.7%) | 1 |
Gestational age at amniocentesis (weeks) | 32.8 (27.8–33.8) | 31 (27.6–32.4) | 0.576 |
Amniotic fluid IL-6 ≥ 2.6 ng/ml | 8/10 (80%) | 8/28 (28.6%) | 0.008 |
Positive amniotic fluid culture | 2/9 (22.2%) | 2/28 (7.1%) | 0.244 |
Amniotic fluid WBC (cells/mm3) ≥ 50 cells/mm3 | 5/10 (50%) | 0/28 (0%) | < 0.001 |
Amniotic fluid glucose (mg/dl) < 14 mg/dl | 6/9 (66.7%) | 1/28 (3.6%) | < 0.001 |
Gestational age at delivery (weeks) | 32.8 (27.9–33.9) | 34.8 (31–38.8) | 0.092 |
Cesarean section | 2/10 (20%) | 3/28 (10.7%) | 0.592 |
Birthweight (g) | 1907.5 (1078.8–2037.5) | 2142.5 (1587.5–2992.5) | 0.047 |
Birthweight percentile | 30.7 (18.5–50) | 32.9 (21.7–48.3) | 0.647 |
Antenatal corticosteroids | 7/10 (70%) | 26/28 (92.9%) | 0.103 |
Tocolytic agents | 4/10 (40%) | 13/28 (46.4%) | 1 |
Composite neonatal morbidity | 7/10 (70%) | 11/28 (39.3%) | 0.144 |
Acute chorioamnionitis | 5/9 (55.6%) | 9/24 (37.5%) | 0.442 |
Chronic chorioamnionitis | 4/9 (44.4%) | 7/24 (29.2%) | 0.438 |
