Table 3 Description of top10 proteins in PPI.
Official symbol | Molecular function | Biological process | Location |
|---|---|---|---|
Gapdh | Oxidoreductase, transferase | Apoptosis, glycolysis, translation regulation | Plasma membrane and cytosol |
Mapk14 | Kinase, serine/threonine-protein kinase, transferase | Apoptosis, stress response, transcription | Nuclear speckles and cytosol |
Jun | Activator, DNA-binding | Transcription, transcription regulation | Nucleoplasm |
Cat | Mitogen, oxidoreductase, peroxidase | Hydrogen peroxide | Vesicles |
Casp3 | Hydrolase, protease, thiol protease | Apoptosis | Nucleoplasm and mitochondria |
Vegfa | Developmental protein, growth factor, Heparin-binding, Mitogen | Angiogenesis, differentiation | Secreted to blood |
Decr1 | Oxidoreductase | Fatty acid metabolism, lipid metabolism | Mitochondria and cytosol |
Cs | Transferase | Tricarboxylic acid cycle | Mitochondria |
Suclg1 | Ligase | Tricarboxylic acid cycle | Mitochondria and plasma membrane |
Tpi1 | Isomerase, lyase | Gluconeogenesis, glycolysis | Nucleoplasm and vesicles |
