Table 9 The regulation of KEGG pathways enriched by den-genes on muscle components.

From: Identification of potential microRNAs and KEGG pathways in denervation muscle atrophy based on meta-analysis

Pathway

Altered after ECS81

NMJ

Ion channel

Connexins

Insulin signaling pathway

 + 

 + 82

Kv4.283

 − 

T cell receptor signaling pathway

 + 

 − 

 − 

 − 

MAPK signaling pathway

 + 

 + 84

K ATP85, Kv2.186, Nav1.587

Connexin 4388

Toll-like receptor signaling pathway

 + 

 + 89

Kv4.2/4.390, TRPV191, K ATP85

Connexin 4392

B cell receptor signaling pathway

 + 

 − 

 − 

 − 

Starch and sucrose metabolism

 + 

 − 

 − 

 − 

Vascular smooth muscle contraction

 − 

 − 

 − 

 − 

Adipocytokine signaling pathway

 − 

 − 

 − 

 − 

Neurotrophin signaling pathway

 + 

 + 93

CLC-494, Kv1.395

 − 

VEGF signaling pathway

 + 

 − 

TRPV496, TRPM7

 − 

  1. NMJ neuromuscular junction, ECS electrical Stimulation, CLC-4 chloride channel 4, TRPV4 transient receptor potential vanilloid 4, TRPM7 transient receptor potential melastatin-subfamily 7.